Lipodystrophy

Generalized Lipodystrophy.

[Mesenteric lipodystrophy].

Mesenteric lipodystrophy is a rare disorder characterized by either focal or diffuse thickening of the mesentery due to chronic inflammation and fibrosis. The etiology and pathogenesis is obscure. Roentgenologic findings help in differential diagnosis with other diseases but they rarely establish the diagnosis. This is made in most cases by laparotomy.

Lipodystrophy = الحثل الشحمي

The lipodystrophies are a heterogeneous group of diseases characterized by generalized or partial loss of subcutaneous fat. In addition to clearly exhibiting selective loss of adipose tissue, patients are also at risk for abnormalities such as insulin resistance, hyperinsulinemia, type 2 diabetes mellitus, hyperlipidemia, glomerulonephritis, and autoimmune disorders. Advances in molecular biolo...

The lipodystrophy syndrome

HIV-associated lipodystrophy includes both clinical as well as metabolic alterations. The most prominent clinical sign is a loss of subcutaneous fat (lipoatrophy) in the face (periorbital, temporal), limbs and buttocks. Peripheral fat loss can be accompanied by an accumulation of visceral fat. Truncal fat increases initially after therapy and then remains stable resulting in relative central ad...

Partial lipodystrophy and dermatomyositis.

In 1978, an 11-year-old boy began to notice proximal weakness in his limbs together with facial erythema; palpebral violaceous edema; and erythematous papules on his elbows, knees, and over the metacarpophalangeal joints. A diagnosis of polymyositis/dermatomyositis was made. He was treated with oral prednisone, which caused the symptoms to disappear promptly. In 1980, proximal weakness, dysphag...